片腕でおこなった運動学習が他方の腕にも学習効果を与える「両腕間転移」を支える神経基盤を明らかにするため, 経頭蓋磁気刺激法により新規力場内での到達運動学習中に一次運動野の神経活動を阻害し, 両腕間転移への影響を検討した。
結果, 一側上肢での運動学習時には非訓練肢を支配する一次運動野を使いながら逐次的に両腕間転移が進むこと, 力場環境の方向により運動学習および両腕間転移の様態が異なることが明らかとなった。
Many previous studies reported that newly acquired skills in one arm transferred to the other arm; however, neural substrates of such intermanual transfer have yet to be clarified. In the current study, to reveal the contribution of the primary cortex (M1) to intermanual transfer of motor adaptation during an arm-reaching task, I disrupted M1 activity during movements by transcranial magnetic stimulation and see the effect on intermanual transfer.
I found that intermanual transfer was mediated by uinlateral M1 controlling the untrained arm, and occurs in a trial-by-trial manner. In addition, motor adaptation of the trained arm and intermanual transfer to the untrained arm were observed depending on the direction of dynamical perturbation during the arm-reaching task.

研究種目 : 若手研究(B)
研究期間 : 2013～2015
課題番号 : 25750267
研究分野 : 神経科学