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KAKEN_16H05215seika.pdf
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Title |
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冠動脈疾患の診療適格化 : 循環器領域でのprecision medicineの実践
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Kana |
カンドウミャク シッカン ノ シンリョウ テキカクカ : ジュンカンキ リョウイキ デノ precision medicine ノ ジッセン
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Romanization |
Kandōmyaku shikkan no shinryō tekikakuka : junkanki ryōiki deno precision medicine no jissen
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Precision medicine in cardiology : personalizing the management in the patients with coronary artery disease
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香坂, 俊
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Kana |
コウサカ, シュン
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Romanization |
Kōsaka, Shun
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Affiliation |
慶應義塾大学・医学部 (信濃町) ・講師
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Research team head
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科研費研究者番号 : 30528659
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宮田, 裕章
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Kana |
ミヤタ, ヒロアキ
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Romanization |
Miyata, Hiroaki
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Affiliation |
東京大学・医学部附属病院・特任教授
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Research team member
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科研費研究者番号 : 70409704
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猪原, 拓
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イノハラ, タク
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Romanization |
Inohara, Taku
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Collaborator
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池村, 修寛
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イケムラ, ノブヒロ
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Ikemura, Nobuhiro
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Collaborator
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庄司, 聡
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ショウジ, サトシ
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Shōji, Satoshi
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Collaborator
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科研費研究者番号 : 00875411
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澤野, 充明
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サワノ, ミツアキ
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Romanization |
Sawano, Mitsuaki
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Affiliation |
慶應義塾大学・医学部 (信濃町) ・助教
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Research team member
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科研費研究者番号 : 00796104
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白石, 泰之
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シライシ, ヤスユキ
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Romanization |
Shiraishi, Yasuyuki
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Affiliation |
慶應義塾大学・医学部 (信濃町) ・助教
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Research team member
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科研費研究者番号 : 00752700
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2020
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科学研究費補助金研究成果報告書
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2019
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本研究の目標は、循環器分野における Precision Medicine (精密医療) を実践し、大規模データベースの発展的な活用を行うことである。具体的には施設レベルでの診療実態や治療成績のベンチマーキングを行い、さらに主要な治療手技である冠動脈インターベンション (PCI) の潜在的リスクとされる出血・腎障害の予測モデルの構築や検証を行い、個別化されたリスクの提示を行っていく。現在、① 患者背景、② 冠動脈血管造影や PCI の術中情報、③ 院内予後・合併症、さらに ④ 退院後長期予後の収集を継続的に実施している。主要な院内予後に関するリスク補正式の現場活用への検討も行われている。
The purpose of the project was to utilize the large-scale procedure-based registry dataset to establish infrastructure for providing 'precision medicine' in the management of patients with coronary artery disease. We aimed to benchmark the performance of PCI (percutaneous coronary intervention; non-surgical procedure that uses a catheter to place a small structure called a stent to open up blood vessels in the heart that have been narrowed by atherosclerosis) for participating institutions, and build risk-models related to adverse outcome during and after the procedure.
We have reported the baseline characteristics and clinical outcomes of patients who underwent PCI in the region (registered roughly 27.000 patients) and compared the information with the registries and database obtained in other countries. In additon, validation of the key in-hospital outcomes were performed, and aim to include the long-term follow-up information within our risk models in the near future.
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研究種目 : 基盤研究 (B) (一般)
研究期間 : 2016~2019
課題番号 : 16H05215
研究分野 : 循環器内科
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Mar 5, 2021 | | インデックス を変更 |
Nov 14, 2022 | | Creator 著者ID,Creator Name,Creator Kana,Creator Romanization,Creator Affiliation,Creator Affiliation (Translated),Creator Role,Creator Link,Abstract 内容,Note 注記 を変更 |
Apr 19, 2024 | | Creator を変更 |
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