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AN00069296-20060300-0001.pdf
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:Mar 11, 2009 |
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Title |
Title |
アレルギー性結膜疾患におけるケモカインの役割
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Kana |
アレルギーセイ ケツマク シッカン ニ オケル ケモカイン ノ ヤクワリ
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Romanization |
arerugiisei ketsumaku shikkan ni okeru kemokain no yakuwari
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Other Title |
Title |
Therole of chemokines in asllergic conjunctival deseases
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Creator |
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高野, 洋之
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Kana |
タカノ, ヨウジ
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Romanization |
Takano, Yoji
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Affiliation |
川崎市立川崎病院眼科 慶應義塾大学医学部眼科学教室
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Affiliation (Translated) |
Ophthalmology, Kawasaki Municipal Hospital, Department of Ophthalmology, Keio University School of Medicine
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慶應医学会
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Kana |
ケイオウ イガッカイ
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Romanization |
Keio igakkai
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Issued (from:yyyy) |
2006
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Name |
慶應医学
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Name (Translated) |
Journal of the Keio Medical Society
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Volume |
83
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Issue |
1
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2006
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Month |
3
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Start page |
1
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6
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Abstract |
Due to changes in environmental factors and lifestyles, the incidence of allergic conjunctival diseases has increased in recent years. Severe allergic conjunctival diseases such as vernal keratoconjunctivitis and atopic keratoconjunctivitis are often complicated by corneal lesions, that often cause severe pain and sometimes decreases in visual acuity, The infiltration of inflammatory cells such as eosinophils and neutrophits observed in the late phase reaction of allergies is important in the pathogenesisof such lesions. Chemokines are key factors in the regulation of the infiltration of such cells to the ocnlar surface. In this article, we review the role of chemokines in allergic onjunctiva)diseases, the role of IL-4 in the regulation of the production of chemokines and possible therapeutic strategies that target chemokines.
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Keyword |
alopic keraloconjunctivitis
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vernal keratoconjunctivitis
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