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KAKEN_23591795seika.pdf
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Title |
Title |
高速スイッチング2重エネルギーCTの基礎的検討と臨床応用
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Kana |
コウソク スイッチング 2ジュウ エネルギー CT ノ キソテキ ケントウ ト リンショウ オウヨウ
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Romanization |
Kosoku suitchingu 2ju enerugi CT no kisoteki kento to rinsho oyo
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Basic study and clinical application of fat kVp switching dual energy CT
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陣崎, 雅弘
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ジンザキ, マサヒロ
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Romanization |
Jinzaki, Masahiro
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Affiliation |
慶應義塾大学・医学部・准教授
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Research team head
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科研費研究者番号 : 80216259
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Name |
今西, 宣晶
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Kana |
イマニシ, ノブアキ
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Romanization |
Imanishi, Nobuaki
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Affiliation |
慶應義塾大学・医学部・准教授
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Research team member
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科研費研究者番号 : 00184820
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田波, 穣
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タナミ, ユタカ
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Romanization |
Tanami, Yutaka
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慶應義塾大学・医学部・助教
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Research team member
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科研費研究者番号 : 00306797
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山田, 稔
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Kana |
ヤマダ, ミノル
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Romanization |
Yamada, Minoru
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Affiliation |
慶應義塾大学・医学部・助教
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Research team member
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科研費研究者番号 : 60365434
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栗林, 幸夫
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Kana |
クリバヤシ, サチオ
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Romanization |
Kuribayashi, Sachio
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Affiliation |
慶應義塾大学・医学部・教授
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Research team member
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科研費研究者番号 : 40102842
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2014
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科学研究費補助金研究成果報告書
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2013
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Abstract |
仮想単色X線CT画像はビームハードニングアーチファクトの抑制効果があることを心筋潅流および腎嚢胞において検証した。仮想単色X線CT画像の70keV画像は、腹部CTで120kVpに比べて画質が良好であること、肝転移においても70keVが至適であることを確認し、70keV画像は120kVpを置換し得ることを示した。また、仮想単純CT像は、CT値は実際の単純CTとほぼ同等で、冠動脈石灰化スコアにおいて有効活用できることを示した。しかし、期待されたヨード強調画像での動脈の石灰化病変の狭窄診断能の向上は得られなかった。今後、メーカーと連携しながら、ヨード強調画像の画質向上に向けて検討を続けて行く。
We clarified that virtual monochromatic spectral (VMS) images obtained at 70 keV had fewer beam-hardening artifacts than those obtained at 120 kVp for images obtained during evaluations of cardiac perfusion and renal cysts. We also showed that the 70 keV images provided both image noise reduction and an improved contrast-noise ratio, compared with the 120-kVp images, in abdominal CT evaluations. Thus, VMS imaging has the potential to replace 120-kVp CT as the standard CT imaging modality. We also showed that virtual non-contrast images provided CT attenuation values that were equivalent to a true unenhanced image, and the coronary artery calcium scores derived from water density images paralleled those obtained using 120-kVp unenhanced images. However, the diagnostic performance of iodine/calcium-based materials for decomposition images used to evaluate severely calcified coronary arteries was not as high as expected. We plan to continue evaluating material decomposition imaging.
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研究種目 : 基盤研究(C)
研究期間 : 2011~2013
課題番号 : 23591795
研究分野 : 医歯薬学
科研費の分科・細目 : 内科系臨床医学・放射線科学
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