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KAKEN_17K20031seika.pdf
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Download
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:875.0 KB
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:Oct 31, 2019 |
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: 355 |
Total downloads since Oct 31, 2019 : 355
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Bio-imaging without targets
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岡, 浩太郎
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オカ, コウタロウ
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Oka, Kōtarō
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慶應義塾大学・理工学部 (矢上)・教授
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Research team head
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科研費研究者番号 : 10276412
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院田, 雅裕
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インダ, マサヒロ
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Inda, Masahiro
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井上, 俊成
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イノウエ, シュンセイ
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Inoue, Shunsei
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遠藤, 実夏
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エンドウ, ミカ
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Endō, Mika
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Collaborator
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2019
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科学研究費補助金研究成果報告書
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2018
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| Abstract |
生命現象を解析する際に様々なイメージング技術が使われており、とりわけ蛍光色素やタンパク質を利用した、事前に見る対象を決めたイメージング技術開発は目覚しい。我々はこの様なBioimaging with targes研究に対して、事前に見る対象を決めないBioimaging without targets研究を提案した。この研究では無染色標本から可視光域でのハイパースペクトルやラマン分光イメージング法により画像を取得し、様々情報処理技法を用いることで、細胞温度の計測や脳地図の自動生成を行うことに成功した。
A variety of imaging techniques are used in analyzing biological phenomena, and in particular, development of imaging techniques targeted for specific molecules in advance using fluorescent dyes and proteins is remarkable. We proposed a Bioimaging without targets study that did not decide, in advance, the target for such a Bioimaging with targes study. In this research, images were acquired from unstained biological specimens (Hela cells and brain slices) by a hyperspectrum camera in the visible light region or Raman spectroscopic imaging method, and various information processing techniques succeeded in measuring cell temperature and automatically generating brain map.
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研究種目 : 挑戦的研究(萌芽)
研究期間 : 2017～2018
課題番号 : 17K20031
研究分野 : 生体生命情報学, 神経科学, 生物物理
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