細径穿刺針から実質臓器の損傷（離開）を生じる圧以下で造影剤注入を行えれば、より実質損傷の少ない臓器内脈管の造影が可能になる。豚肝の固定注入圧（30、40、50、60、70、80、90mmHg）での実質離開頻度はそれぞれ0%、7%、16%、37%、40%、100%、70%の確率であったことから、豚肝の実質損傷は注入圧40mmHg以上で発生し、注入圧30mmHgでは実質損傷を生じることなく胆管、門脈等の造影が行えると考えられた。脾臓、腎臓でも固定圧での実質離開頻度を観察し、それぞれ40mmHg、50mmHg以下に注入圧を設定すれば、実質損傷を生じにくいとの結果を得た。
If the contrast medium can be injected from the fine needle at an injection pressure lower than the pressure that causes damage (dehiscence) of the parenchymal organ, it is possible to visualize the intra-organ vessel with less parenchymal damage. The probability of parenchymal dehiscence caused by injection at a fixed pressure (30, 40, 50, 60, 70, 80, 90 mmHg) of pig liver is 0%, 7%, 16%, 37%, 40%, 100%, 70%, respectively. Therefore, it was considered that the parenchymal dehiscence to the porcine liver occurred at an injection pressure of 40 mmHg or higher, and that bile ducts, portal veins, etc. could be visualized without causing parenchymal dehiscence at an injection pressure of 30 mmHg. The frequency of parenchymal dehiscence at fixed pressure was also observed in the spleen and kidney, and it was found that if the injection pressures were set to 40 mmHg and 50 mmHg or less, respectively, parenchymal damage was unlikely to occur.

研究種目 : 基盤研究 (C) (一般)
研究期間 : 2017～2020
課題番号 : 17K10452
研究分野 : インターベンショナルラジオロジー (IVR)