超高齢社会を迎え, 加齢に伴う脂肪増加(メタボリックシンドローム,メタボ)だけでなく, 筋肉減少(ロコモティブシンドローム, ロコモ)評価・対応が必要である。そこでメタボ診断基準である内臓脂肪面積測定のための臍部CT同一画像を用いて, 腹部筋肉面積およびその質の評価としてのCT値を評価し, 運動器疾患・代謝疾患との関連を検討した。
既報より, 腹部筋肉(とくに大腰筋)の代謝異常との関連を予想したが, 代謝性疾患, メタボ評価には内臓脂肪がより有用であった。一方で, ロコモ(特に変形性膝関節症)評価には, 全身や四肢筋肉量より腹部筋肉(特に脊柱起立筋)が有用で, メタボとロコモの同時評価のための有用な知見を得られた。
Emerging super-aging societies have an urgent need for preventive assessment and therapy for both metabolic syndrome (MS) arsing from fat gain, and locomotive organ disorders (LODs) arising from muslce loss, as a common aging process. Therefore, this study investigated the association of abdominal trunk muscle with MS and LODs using computed tomography images at the level of the umbilicus primarily taken for the assessment of visceral adiposity (a primordial marker for MS).
Unlike our primary hypothesis, there was no superior association of abdominal trunk muscle with MS, comapared with visceral adiposity. However, smaller area/lower attenuation value of the abdominal trunk (especially paraspinal) muscles, rather than appendicular or total lean mass, was associated with LODs (especially knee osteoarthritis). Our finding suggests that a simultaneous assessment of abdominal trunk muscle with visceral adiposity enables us to assess both MS and LODs in the clinical setting.
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