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Item Type Article
ID
0402-1501-0382  
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Title
Title Comprehensive analysis of microbes and metabolites in human tear fluids  
Kana  
Romanization  
Other Title
Title ヒト涙液中の微生物および代謝物質の網羅的解析  
Kana ヒト ルイエキチュウ ノ ビセイブツ オヨビ タイシャ ブッシツ ノ モウラテキ カイセキ  
Romanization Hito ruiekichu no biseibutsu oyobi taisha busshitsu no morateki kaiseki  
Creator
Name 村上, 慎之介  
Kana ムラカミ, シンノスケ  
Romanization Murakami, Shinnosuke  
Affiliation 慶應義塾大学大学院政策・メディア研究科後期博士課程  
Affiliation (Translated) Doctoral program, Graduate School of Media and Governance, Keio University  
Role  
Link  

Name 馬場, 藤貴  
Kana ババ, フジタカ  
Romanization Baba, Fujitaka  
Affiliation 慶應義塾大学先端生命科学研究所所員  
Affiliation (Translated) Staff, Institute for Advanced Biosciences, Keio University  
Role  
Link  

Name Aw, Wanping  
Kana アウ, ワンピン  
Romanization  
Affiliation 慶應義塾大学大学院政策・メディア研究科研究員  
Affiliation (Translated) Project researcher, Graduate School of Media and Governance, Keio University  
Role  
Link  

Name 福田, 真嗣  
Kana フクダ, シンジ  
Romanization Fukuda, Shinji  
Affiliation 慶應義塾大学大学院政策・メディア研究科特任准教授  
Affiliation (Translated) Project associate professor, Graduate School of Media and Governance, Keio University  
Role  
Link  

Name 曽我, 朋義  
Kana ソガ, トモヨシ  
Romanization Soga, Tomoyoshi  
Affiliation 慶應義塾大学環境情報学部教授  
Affiliation (Translated) Professor, Faculty of Environment and Information Studies, Keio University  
Role  
Link  

Name 藤島, 浩  
Kana フジシマ, ヒロシ  
Romanization Fujishima, Hiroshi  
Affiliation 鶴見大学歯学部附属病院眼科教授  
Affiliation (Translated) Professor, Department of Ophthalmology, Tsurumi University Dental Hospital  
Role  
Link  

Name 冨田, 勝  
Kana トミタ, マサル  
Romanization Tomita, Masaru  
Affiliation 慶應義塾大学環境情報学部教授  
Affiliation (Translated) Professor, Faculty of Environment and Information Studies, Keio University  
Role  
Link  
Edition
 
Place
藤沢  
Publisher
Name 慶應義塾大学湘南藤沢学会  
Kana ケイオウ ギジュク ダイガク ショウナン フジサワ ガッカイ  
Romanization Keio gijuku daigaku Shonan Fujisawa gakkai  
Date
Issued (from:yyyy) 2015  
Issued (to:yyyy)  
Created (yyyy-mm-dd)  
Updated (yyyy-mm-dd)  
Captured (yyyy-mm-dd)  
Physical description
 
Source Title
Name Keio SFC journal  
Name (Translated)  
Volume 15  
Issue 1  
Year 2015  
Month  
Start page 382  
End page 400  
ISSN
13472828  
ISBN
9784877384654  
DOI
URI
JaLCDOI
10.14991/003.00150001-0382
NII Article ID
 
Ichushi ID
 
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Doctoral dissertation
Dissertation Number  
Date of granted  
Degree name  
Degree grantor  
Abstract
Lacrimal fluids are important in protecting the eyes from environmental factors and also possess antimicrobial abilities. Although human tear fluid metabolites have been reported, the relationships between these metabolites and eye diseases have yet to be elucidated. In addition, the microbial composition of human tear fluids has not been investigated yet, even though numerous human microbiome analyses of various body sites have been reported. Therefore, microbiome and metabolome analyses of human tear fluids from healthy subjects and atopic keratoconjunctivitis (AKC) patients were conducted. The current study suggested that lactic acid bacteria in tear fluids might have a potential to prevent pathogenesis of AKC, whereas o-acetylcarnitine reduction and urea increment might be involved in AKC pathogenesis.
 
Table of contents

 
Keyword
tear fluid  

atopic keratoconjunctivitis  

microbiome analysis  

metabolome analysis  

lactic acid bacteria  
NDC
 
Note
特集 世界を救え : SFCバイオの挑戦#研究論文
 
Language
英語  

日本語  
Type of resource
text  
Genre
Journal Article  
Text version
publisher  
Related DOI
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Last modified date
Sep 20, 2023 13:18:06  
Creation date
Jun 29, 2017 17:01:16  
Registerd by
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History
Jul 30, 2019    著者 を変更
Sep 20, 2023    JaLCDOI を変更
 
Index
/ Public / Shonan Fujisawa / Keio SFC journal / 15(1) 2015
 
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