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KAKEN_24591666seika.pdf
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Download
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:349.4 KB
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| Last updated |
:Apr 11, 2016 |
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: 561 |
Total downloads since Apr 11, 2016 : 561
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| Title |
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毛髪を成長・維持させる重要遺伝子のノックダウンマウス作製による網羅的同定
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| Kana |
モウハツ オ セイチョウ・イジサセル ジュウヨウ イデンシ ノ ノックダウン マウス サクセイ ニ ヨル モウラテキ ドウテイ
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Mohatsu o seicho ijisaseru juyo idenshi no nokkudaun mausu sakusei ni yoru morateki dotei
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Conprehensive identification of important genes related to growing and maintaining the hair using knock down mice.
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渋谷, 和憲
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シブヤ, カズノリ
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Shibuya, Kazunori
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慶應義塾大学・医学部・助教
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Research team head
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科研費研究者番号 : 90296723
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2015
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科学研究費補助金研究成果報告書
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2014
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| Abstract |
加齢とともに毛髪が薄くなったり, 細くなるなどの悩みを抱える人が非常に多く存在する。そこで毛髪を維持・成長させる遺伝子を遺伝子改変マウス(ノックダウンマウス)を用いて探索する実験を行った。その結果, 数匹の遺伝子改変マウスを作製することには成功したが期待したような毛髪に変化のある表現型は観察されなかった。
Many people hold a trouble of hair becoming thin with aging. Then, the experiment which searches for the gene which maintains and grows up hair using a genetically engineered mouse (knockdown-mouse) was conducted. As a result, the expected phenotype which has change in hair was not observed, although it succeeded in producing a genetically engineered mouse.
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研究種目 : 基盤研究(C)
研究期間 : 2012～2014
課題番号 : 24591666
研究分野 : 分子生物学
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