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KAKEN_17K16703seika.pdf
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磁気共鳴画像法を用いた肩甲帯周囲筋の三次元定量的解析
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ジキ キョウメイ ガゾウホウ オ モチイタ ケンコウタイ シュウイキン ノ サンジゲン テイリョウテキ カイセキ
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Jiki kyōmei gazōhō o mochiita kenkōtai shūikin no sanjigen teiryōteki kaiseki
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Three-dimensional quantitative assessment of the rotator cuff muscle using magnetic resonance imaging
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松村, 昇
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マツムラ, ノボル
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Matsumura, Noboru
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慶應義塾大学・医学部 (信濃町) ・講師
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Research team head
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科研費研究者番号 : 70383859
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2020
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科学研究費補助金研究成果報告書
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2019
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本研究はMRIの三次元シークエンスで撮影された画像を用いて肩甲帯周囲筋の形態と脂肪浸潤の詳細な定量解析を行い、肩甲帯周囲筋の形態を明らかにすること、画像所見から患者の正確な予後予測を行うこと、筋変性メカニズムを解明することを目的とした。対照群と比較して腱断裂が生じた筋では筋内脂肪含有率が高値、筋体積が低値を示しており、また広範囲断裂においては小円筋が代償性に筋体積高値を示していた。本研究結果は過去の知見と矛盾せず、MRIを用いて筋変性を定量的に評価することが可能であった。また陳旧性腱板断裂においては経時的に筋萎縮が進行するものの、筋内脂肪浸潤の著明な進行は生じないことが明らかとなった。
In cases with rotator cuff tears, muscular degeneration is known to be a predictor of irreparable tears and poor outcomes after surgical repair. Fatty infiltration and volume of the whole muscles constituting the rotator cuff were quantitatively assessed using 3-dimensional magnetic resonance imaging. Intra- and inter-rater reliabilities were regarded as excellent for both fat fraction and muscle volume. Tendon rupture adversely increased the fat fraction value of the respective rotator cuff muscle. The massive tear group showed significantly decreased muscle volume of infraspinatus and increased volume of teres minor. Three-dimensional measurement could evaluate fatty infiltration and muscular volume with excellent repruducibility. In cases with rotator cuff tears, fatty infiltration of the torn muscle is thought to cause in its early phase, and muscle atrophy appears to gradually progress.
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研究種目 : 若手研究 (B)
研究期間 : 2017~2019
課題番号 : 17K16703
研究分野 : 整形外科学
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